European Cytokine Network
MENUInterferon-g and its functional receptors overexpression in benign prostatic hyperplasia and prostatic carcinoma: parallelism with c-myc and p53 expression. Volume 11, numéro 1, March 2000
Illustrations
Department of Cell Biology and Genetics, University of Alcalá, E-28871 Alcalá de Henares, Madrid, Spain. ricardo.paniagua@alcala.es
- Mots-clés : Interferon-g (IFN-g), interferon-g receptor-a (IFN-g-Ra), interferon-g receptor-b (IFN-Rb), p53, c-myc, human prostate, cancer.
- Page(s) : 119-27
- Année de parution : 2000
INTRODUCTION Interferons are a group of proteins that trigger multiple responses including prevention of viral replication, inhibition of cell growth, and modulation of cell differentiation [1]. They also show anti-tumour properties, and are currently used for the treatment of cancers [2]. Type I interferons include interferon-alpha (IFN-alpha, leukocyte-derived) and interferon-beta (IFN-beta, fibroblast-derived), which are produced [...]