European Cytokine Network
MENUInterleukin - 1 primes interleukin-8-stimulated chemotaxis and elastase release in human neutrophils via its type I receptor Volume 8, numéro 2, June 1997
Illustrations
- Mots-clés : interleukin-1, interleukin-8, priming, IL-1 receptors, neutrophils, elastase release, chemotaxis
- Page(s) : 173-8
- Année de parution : 1997
INTRODUCTION Interleukin-1 (IL-1) is a pleiotropic inflammatory cytokine which plays a central role in immunity and inflammation. The spectrum of action of IL-1 encompasses activity on cells of hematopoietic origin, from immature precursors to mature leukocytes, as well as on components of the vessel wall and cells of mesenchymal and epithelial origin [1, 2]. In addition to a direct effect on target cells, the induction of [...]