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European Cytokine Network

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Interleukin - 1 primes interleukin-8-stimulated chemotaxis and elastase release in human neutrophils via its type I receptor Volume 8, numéro 2, June 1997

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INTRODUCTION Interleukin-1 (IL-1) is a pleiotropic inflammatory cytokine which plays a central role in immunity and inflammation. The spectrum of action of IL-1 encompasses activity on cells of hematopoietic origin, from immature precursors to mature leukocytes, as well as on components of the vessel wall and cells of mesenchymal and epithelial origin [1, 2]. In addition to a direct effect on target cells, the induction of [...]