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European Cytokine Network

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Proinflammatory interferon-gamma - inducing monokines (interleukin-12, interleukin-18, interleukin-15) - serum profile in patients with systemic lupus erythematosus Volume 13, numéro 3, September 2002

Auteurs
Department of Hematology, Medical University of Lodz, 93-513 Lodz, Pabianicka 62, Poland.
  • Page(s) : 364-8
  • Année de parution : 2002

INTRODUCTION In recent years, several novel proinflammatory cytokines with possible roles in SLE pathogenesis have been discovered. Among them, IL-12, IL-18 and IL-15 levels have been found to be elevated in the serum and/or plasma from SLE patients [1-4]. However, the association between these cytokines levels and disease activity as well as particular clinical and laboratory symptoms of SLE, have not been so far fully investigated. [...]