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Role of interleukin-6 in a non-septic shock model induced by zymosan. Volume 10, numéro 2, June 1999

Auteurs
Institute of Pharmacology, School of Medicine, University of Messina, Piazza XX Settembre n° 4, 98123 Messina Italy.
  • Page(s) : 191-204
  • Année de parution : 1999

INTRODUCTION Zymosan, a product consisting of purified baker's yeast ghost cells, has been reported to elicit an acute peritonitis and multiple organ failure in experimental animals, characterized by functional and structural changes in the liver, intestine, lung and kidneys [1-5]. The organ dysfunction in zymosan-treated animals may, in part, be dependent on bacterial translocation [2, 3, 6]. The role of the production of [...]