European Cytokine Network
MENUAnti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis Volume 14, numéro 1, March 2003
Illustrations
Vincent L. Butty, Pascale Roux-Lombard, Jorge Garbino, Jean-Michel Dayer, Bara Ricou, the Geneva Sepsis Network
Division of Surgical Intensive Care, Department of Anesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, 1211 Geneva 14, Switzerland.
- Page(s) : 15-9
- Année de parution : 2003
INTRODUCTION Severe sepsis is associated with a significant degree of morbidity and mortality in intensive care units (ICU) [1, 2]. It can lead to organ failure along with hemodynamic instability, accounting for the potentially fatal outcome of a septic episode [3]. Tumor necrosis factor-alpha(TNF-alpha), interleukin-1 (IL-1) and IL-6 seem to play a key role in the pathogenesis of sepsis. IL-6 is considered [...]