European Cytokine Network
MENUAnalysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line. Volume 10, numéro 4, December 1999
Illustrations
Flanders Interuniversity Institute for Biotechnology, Dept VIB09, Medical Protein Research, Faculty of Medicine, University of Ghent, K.L. Ledeganckstraat 35, B-9000 Ghent, Belgium.
- Page(s) : 549-56
- Année de parution : 1999
INTRODUCTION The maintenance of food stores and energy homeostasis is established through the effect of an expanding array of (neuro)peptides and neurotransmitters. They constitute a complex interaction network in which leptin, a hormone primarily secreted by white adipose tissue, plays a major role that is documented by several rodent obesity models [1-3]. After transportation through the blood-brain barrier, the satiety [...]