European Cytokine Network
MENUCirculating macrophage colony stimulating factor as a marker of tumour progression Volume 13, numéro 1, March 2002
Illustrations
Raymond S. McDermott, Laurent Deneux, Véronique Mosseri, Jacques Védrenne, Krishna Clough, Alain Fourquet, José Rodriguez, Jean-Marc Cosset, Xavier Sastre, Philippe Beuzeboc, Pierre Pouillart, Susy M. Scholl
Médecin-Spécialiste, Institut Curie, 26, rue d'Ulm, 75248 Paris Cedex 05, France.
- Page(s) : 121-7
- Année de parution : 2002
INTRODUCTION Colony stimulating factor is a polypeptide growth factor which regulates the survival, proliferation and differentiation of mononuclear phagocytes [1]. Synthesized by many different cell types including fibroblasts, bone marrow stromal cells, lymphocytes and activated macrophages, CSF-1 acts through a high affinity tyrosine kinase receptor encoded by the c-fms proto-oncogene [2], exerting chemotactic effects on precursors of [...]