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Role of cytokines in the modulation of nitric oxide production by cyclic AMP. Volume 12, numéro 1, March 2001

Auteur
Laboratory of Molecular Immunopharmacology, Institute of Pharmacology, Academy of Sciences, Vídenská 1083, 14220 Prague, Czech Republic.
  • Page(s) : 22-32
  • Année de parution : 2001

INTRODUCTION Adenosine and its natural derivative cyclic 3',5'-adenosine monophosphate (cAMP) are important factors of intracellular signaling. The adenosine/cAMP pathways thus influence a variety of biochemical processes which have been implicated in the control of inflammation [1], as well as in the pathogenesis of many diseases, for example myocardial ischaemia, acute renal failure, pancreatic disorders, schizophrenia, epilepsy, Alzheimer's [...]