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 Printable version |
Sickle cell disease: from molecular aspects to clinical practice. A case report and a literature analysis |
Annales de Biologie Clinique. Volume 69, Number 6, 679-84, Novembre-Décembre 2011, Biologie au quotidien
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 Résumé
Texte intégral
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Author(s) : Sophie Huynh-Moynot, Jean-Clair Moynot, Diane Commandeur, Marc Danguy Des Deserts, Étienne Montelescaut, Nadia Kenane, Isabelle Drouillard |
Summary : Sickle cell disease is the genetic disease most frequently detected at birth in France. The comprehension and knowledge of its pathophysiology allow to establish the principles of management for the drepanocytic patient, especially in the perioperative phase. In the light of recent recommendations published for anesthesia of a drepanocytic adult, this clinical case revealed allows to reexamine that subject, with a focus on biological aspects, which are transfusional strategy and antibioprophylaxy. The presented observation is a concrete feature of daily collaboration between clinician and biologist, which is an essential point of the ISO standard EN 15189 concerning laboratories’ accreditation. |
Keywords : sickle cell disease, anesthesia, intensive care unit, transfusion, antibioprophylaxy, coelioscopy, acute chest pain, vaso-occlusive crisis |
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