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Cytogenetic markers in chronic lymphocytic leukaemia


Annales de Biologie Clinique. Volume 68, Number 3, 273-6, mai-juin 2010, synthèse

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Author(s) : Florence Nguyen-Khac

Summary : Recurrent cytogenetic abnormalities observed in chronic lymphocytic leukaemia (CLL) are frequent. They involve the 13q, 11q, 12q, 17p and 6q chromosomal regions, by decreasing order of frequency. These abnormalities can be isolated or associated. They can also appear during the course of the disease. Some of them, as 11q and 17p deletions, give prognostic information for the management of CLL patients.

Keywords : cytogenetics, chronic lymphocytic leukemia

 

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