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Annales de Biologie Clinique. Volume 62, Number 5, 578-82, Septembre-Octobre 2004, pratique quotidienne

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Author(s) : S Ferchichi , A Kassab-Chekir , S Laradi , D Amira , Z Jaidane , H Chahed , E Chahed , L Chkioua , H Ben Limam , S Bouchoucha , A Miled

Summary : Toxic epidermal necrolysis (TEN) is a rare drug-induced disease characterized by extensive epidermal destruction. We reported here a case of Lyell syndrome wich happened few hours later after treatment associating lincomycine chlorhydrate with nonsteroidol anti-inflamatory drugs. The 28-year-old female patient developed many visceral complications with biochemical and haematological disorders. This syndrome is a dermatological emergency whose vital prognosis is displayed.

Keywords : Lyell syndrome, toxic epidermal necrolysis, drug