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Is detection of schizocytes by computerised image analysis accurate ?


Annales de Biologie Clinique. Volume 59, Number 2, 165-8, Mars - Avril 2001, Articles originaux

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Author(s) : S. Salignac, C. Campedel, P. Bordigoni, T. Lecompte, J.-F. Lesesve

Summary : Schistocytes result from red cell fragmentation. The identification of the schistocytes is critical for decisions on appropriate management of the patients. Currently, a systematic approach to the counting method remains rewarded. We programmed a computer image analysis device (Q-Win, Leica) in order to detect fragmented red cells. A good correlation between the computer and a well-trained biologist was found after minor modifications of the computer's results. Image analysis should reduced the biologist-to-biologist variation and improve the identification and enumeration of the schistocytes.

Keywords : Schizocytes - Image analysis.

 

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