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 Printable version |
Evaluation of the Immulite 2000 Toxoplasma quantitative IgG® et Toxoplasma IgM® for the serological diagnosis of human toxoplasmosis |
Annales de Biologie Clinique. Volume 59, Number 2, 157-64, Mars - Avril 2001, Articles originaux
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 Résumé
Article gratuit
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Author(s) : A. Dao, B. Fortier |
Summary : Four hundred and ninety five human sera with clinical and biological data were tested for the evaluation of Immulite 2000 Toxoplasma Quantitative IgG® and Immulite 2000 Toxoplasma IgM® produced by Diagnostic Products Corporation (Los Angeles, USA) for the diagnosis of human toxoplasmosis. The results of these kits were compared to those of the University Hospital of Nancy where the reference assays were Enzygnost Toxoplasmosis IgG and Enzygnost Toxoplasmosis IgM (Berhing-Dade, Germany), Toxoscreen (bioMérieux, France), ISAgA Plus (IgM et IgA) (bioMérieux, France). The sensitivity and the specificity of IgG detection by Immulite 2000 Toxoplasma Quantitative IgG® were 98% and 100%, respectively. The high sensitivity of IgM detection by Immulite 2000 Toxoplasma IgM was adapted to the early diagnosis of toxoplasmic primo-infection and to the pediatric diagnosis or follow-up of congenital toxoplasmosis but could reveal IgM a long time after primary infection. |
Keywords : Toxoplasmosis - Serology. |
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