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Comparative evaluation of a latex agglutination test, two Elisa kits and a western blot kit for the serodiagnosis of human trichinellosis |
Annales de Biologie Clinique. Volume 60, Number 1, 79-83, Janvier - Février 2002, Articles originaux
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 Résumé
Article gratuit
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Author(s) : S. Andiva, H. Yera, S. Haeghebaert, C. Tourte-Schaefer, J.-F. Magnaval, J. Dupouy-Camet |
Summary : Serology is a helpful test for the diagnosis of human trichinellosis because clinical signs of this disease (fever and myalgias) are non specific. A lot of techniques have been studied but very few are commercialized and have been comparatively evaluated. We report here the performances of 4 commercially available kits: two Elisa tests, one western blot test & one latex agglutination test. The specifity and sensitivity of the different tests were assayed on 60 sera from patients with a proven trichinellosis and on 70 controls. The four tests had a 100% sensitivity. The specificity was of 98.6% for the western blot, of 93% for the latex agglutination test and of 87 & 77% for the two Elisa tests. Cross reactions are mainly observed in patients with other helminthic infections. |
Keywords : Trichinellosis - Human - Elisa - Western blot - Latex - Trichinella. |
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