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 Printable version |
Calciotropic hormones and osteoporosis |
Annales de Biologie Clinique. Volume 55, Number 4, 311-8, Juillet - Août 1997, Revues générales
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 Résumé
Article gratuit
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Author(s) : C. Cormier, J.-C. Souberbielle, C. Kindermans |
Summary : Calcium homeostasis maintenance is controlled by calciotropic hormones action. Bone is a major target tissue for PTH and calcitriol. Excess in at least one of the two hormones may be deleterious to bone, leading to osteoporosis. Calciotropic hormones must of course be measured if an ano-maly of serum calcium/phosphate is discovered. However, when the degree of osteopenia is discordant with the risk factors of osteoporosis in a given patient, it may be of value to measure calciotropic hormones, even if serum calcium/phosphate are normal. Previously undiscovered cause(s) for secon-dary osteoporosis may be diagnosed which, if untreated, may impair the effi-cacy of antiresorptive treatments (estrogens, bisphosphonates,…). Whether to measure calciotropic hormones or not in other less-defined groups of osteopo-rotic patients remains both debatable and debated. |
Keywords : Parathyroid hormone – Vitamin D – Calcitonin – Osteoporosis. |
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