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Annales de Biologie Clinique

Triple fungal infection in a patient with liver cirrhosis Volume 70, issue 1, Janvier-Février 2012


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Laboratoire de parasitologie-mycologie, Institut de microbiologie, Centre de biologie pathologie,, Service de réanimation médicale, Pôle de réanimation,, Service de gastro-entérologie et hépatologie, Pôle de spécialités médicales, CHRU de Lille
  • Key words: triple fungal infection, Candida albicans, Aspergillus fumigatus, Pneumocystis jirovecci, liver cirrhosis
  • DOI : 10.1684/abc.2011.0654
  • Page(s) : 89-92
  • Published in: 2012

The prevalence of invasive mycoses is increasing, especially among patients who are immunocompromised or hospitalized with serious underlying diseases. Such infections are associated with a high morbidity and significant mortality, requiring early diagnosis and appropriate treatment but also an optimal prophylaxis in patients with high risk factors. We report a case of triple fungal infection including an invasive pulmonary aspergillosis by Aspergillus fumigatus, a candidemia by Candida albicans and a Pneumocystis pneumonia. The overall clinical picture of this patient was liver cirrhosis with medical history of immunosuppressive treatment for Crohn disease and a non-hodgkin lymphoma. There was no antifungal prophylaxis for this patient. Under treatment, the issue was unfavourable with multivisceral failure.