JLE

Annales de Biologie Clinique

MENU

Biomarkers of vascular calcifications: what are analytical limits to apply “research-grade” diagnostic kits into daily practice? Volume 73, issue 3, Mai-Juin 2015

Authors
1 Département de biochimie et d’hormonologie, CHRU de Montpellier, U 1046 Inserm, Université de Montpellier 1, Montpellier, France

A better knowledge of physiopathologic mechanisms responsible for vascular calcification leads to emerging biological markers of calcifications. The use of these biomarkers in daily practice requires both clinical and analytical validation. This latter point is of particular importance to implement “research-grade” diagnostic kits into daily practice. Data in the literature underline the lack of method standardization and the non-transferability of results. Depending on the method used, important biological associations might be hidden.