Annales de Biologie Clinique
MENUImmunotherapy-induced hypothyroidism A report of melanoma treated by ipilimumab and nivolumab Volume 76, issue 3, Mai-Juin 2018
Figures
1 Department of endocrinology, University Hospital Bordeaux, France
2 Department of dermatology, University Hospital Bordeaux, France
3 Department of nuclear medicine, University Hospital Bordeaux, France
4 Department of pharmacology, University Hospital Bordeaux, France
5 Groupe de biologie spécialisée, Société française de médecine nucléaire, Paris, France
a Participation équivalente au travail
- Key words: hypothyroidism, thyroiditis, ipilimumab, nivolumab, melanoma
- DOI : 10.1684/abc.2018.1350
- Page(s) : 326-8
- Published in: 2018
We report the case of a patient treated by ipilimumab and nivolumab for a metastatic melanoma. After a mild clinical thyroiditis and a transient biological hyperthyroidism she rapidly demonstrated a peripheral hypothyroidism with appearance of antibodies against thyroperoxidase and thyroglobulin.