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Annales de Biologie Clinique

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Quantitative measurement of urinary proteins in 2018: advantages, disadvantages, limits Volume 76, issue 6, Novembre-Décembre 2018

Authors
Edith Bigot-Corbel Pour le groupe de travail SFBC, SFNDT, SNP « Actualités sur les protéinuries » 1 *
1 Laboratoire de biochimie, Centre hospitalier universitaire de Nantes, France
2 Laboratoire de biochimie, Hôpital européen Georges Pompidou, AP-HP, Paris, France
* Tirés à part
  • Key words: urinary protein, measurement methods
  • DOI : 10.1684/abc.2018.1389
  • Page(s) : 627-31
  • Published in: 2018

Today, there is no reference method for the measurement of urinary proteins. The difficulties are that urine is a very complex biological fluid, and that there are a high intra-and inter-individual variability in the protein excretion rate. Progress has been made during the last thirty years, but high analytical variability persists among the colorimetric or turbidimetric methods used for urinary proteins measurement.