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Annales de Biologie Clinique

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Association between the percentages of typical forms, acrosome abnormalities and the multiple anomalies indices: potential quality indicators? Volume 70, issue 1, Janvier-Février 2012

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Authors
Laboratoire de biologie polyvalente, Unité de biologie de la reproduction et d’assistance médicale à la procréation, Hôpital Louis Pasteur, Le Coudray

In addition to NF EN ISO 15189, the second version of “GBEA AMP”, published in the official journal of the French Republic, had set for “AMP” exams, the actions to be implemented in order to achieve an efficient quality management system. As part of continuous improvement of quality, and besides our external and internal quality systems, we have been developping indicators that will allow an early detection of potential drifts within operators performing sperm morphology testing. We have extracted nearly 1900 sperm morphology tests from our database. These tests were performed by three operators. The analysis of the data collected has shown a cross correlation between the percentages of typical forms, malformative acrosomes and “MAI”. We have been using these correlations as quality indicators in our laboratory in order to highlight any potential drift in reading sperm morphology tests.