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(Neo)adjuvant chemotherapy of resected colorectal cancer liver metastases


Hépato-Gastro. Volume 19, Number 2, 77-83, Février 2012, Mini-revue

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Author(s) : Astrid Lièvre, Frédérique Peschaud, Emmanuel Mitry

Summary : Colorectal cancer (CRC) liver metastases (LM) are very common but only 20 to 30% of them will be resectable with, in this case, prolonged survival and a possibility to be cured. Their surgical resection should be systematically discussed in multidisciplinary meeting and be re-evaluated when a response to induction chemotherapy has been observed for LM that were not initially resectable. Recurrence, especially in the liver, are common. Perioperative chemotherapy with FOLFOX reduces the risk of recurrence of resectable LM but expose to the risk of missing metastases that can make their resection a problem.

Keywords : colorectal cancer, liver metastases, surgery, chemotherapy

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