John Libbey Eurotext




Cord blood stem cells: current use and perspectives in regenerative medicine
MT / médecine de la reproduction, gynécologie et endocrinologie. Volume 11, Number 1, 28-34, janvier-février 2009, Revue
Résumé Article gratuit
Author(s) : Eliane Gluckman
Summary : Cord blood is a major source of stem cells for hematopoietic stem cell transplants in children and adults. It is collected at birth from the placenta by catheterization of the umbilical veins. After collection, it is tested, processed and cryopreserved in liquid nitrogen. Banks have developed world wide for providing cord blood for unrelated hematopoietic stem cell transplant. Currently more than 400,000 units have been collected and more than 20,000 patients with malignant and non-malignant disorders have been transplanted. Cord blood has the major advantage of immediate availability and less stringent necessity of HLA identity. Transplants with one or HLA differences give the same survival than transplants performed with an HLA identical bone marrow donor. It also becomes more and more apparent that cord blood contains also non-hematopoietic stem cells, which could be used for regenerative medicine.
Keywords : umbilical cord blood, hematopoietic stem cells, cord blood banking

Cord blood stem cells: current use and perspectives in regenerative medicine