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Narrow-band ultraviolet B phototherapy for early stage mycosis fungoides


European Journal of Dermatology. Volume 18, Number 6, 660-2, Novembre-Décembre 2008, Therapy

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Author(s) : Ting Xiao, Li-Xin Xia, Zhen-Hai Yang, Chun-Di He, Xing-Hua Gao, Hong-Duo Chen

Summary : Recently there have been some reports concerned the treatment of early stage mycosis fungoides (MF) with narrow-band ultraviolet B (NB-UVB) phototherapy. In most of the previous reports, NB-UVB phototherapy was given three times a week on non-consecutive days. Our aim was to evaluate the effect of a twice weekly regimen of NB-UVB phototherapy in the treatment of early-stage MF. Eight patients with early stage MF received NB-UVB phototherapy twice weekly. Six patients (75%) had a complete response in a mean of 23.4 treatments, two (25%) had a partial response. Upon discontinuation of treatment, four patients with complete response relapsed in a mean time to relapse of 5 months. The twice weekly regimen of NB-UVB phototherapy is effective and well-tolerated in the treatment of early stage MF.

Keywords : mycosis fungoides, narrow-band ultraviolet B, phototherapy

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