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Three cases of cutaneous phaeohyphomycosis by Exophiala jeanselmei


European Journal of Dermatology. Volume 18, Number 3, 313-6, May-June 2008, Clinical report

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Author(s) : M Covadonga Martínez-González, M Magdalena Verea, David Velasco, Felipe Sacristán, Jesús Del Pozo, Jesús García-Silva, Eduardo Fonseca

Summary : Cutaneous phaeohyphomycosis is a rare opportunistic fungal disease, knowledge of which is important because of the increase in organ transplantation, aggressive treatments for malignancies, and chronic use of corticosteroids. We report 3 cases of cutaneous phaeohyphomycosis: two patients treated with oral corticosteroids and one elderly woman with multiple hospitalizations. They showed several different clinical appearances. Histopathologically, the fungal infection affected the dermis and subcutis in all cases and in one of them, also the epidermis. Exophiala jeanselmei was isolated from the purulent exudate in the three cases. Good response was obtained with surgical and antifungal treatment.

Keywords : Exophiala jeanselmei, opportunistic fungal infection, immunosuppressed patients, phaeohyphomycosis

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