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Multicentric Bowen disease in linear porokeratosis


European Journal of Dermatology. Volume 17, Number 5, 439-40, September-October 2007, Clinical report

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Author(s) : Emmanuella Guenova, Wolfram Hoetzenecker, Gisela Metzler, Martin Röcken, Martin Schaller

Summary : Linear porokeratosis is a genodermatosis, caused by a clonal proliferation of keratinocytes along the lines of Blaschko. This type of porokeratosis is particularly susceptible to malignant degeneration e.g. to Bowen disease, a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Here we report a case of linear porokeratosis on the left leg of a 56-year-old man, complicated with two lesions of multicentric Bowen disease.

Keywords : Bowen disease, linear porokeratosis, malignant degeneration

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