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Efficiency of topical imiquimod 5% cream in the management of chronic radiation dermatitis with multiple neoplasias


European Journal of Dermatology. Volume 16, Number 1, 56-8, January-February 2006, Therapy

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Author(s) : Michael M Sachse, Jutta Zimmermann, Friedrich A Bahmer

Summary : The immune response modifier imiquimod 5% cream (Aldara ®) was locally applied to an extensive thoracic chronic radiation dermatitis for 2 weeks on a once daily basis. After moderate to severe irritative reactions with erythema and crusted erosions, areas cleared up within 4 weeks. The patient has now been in complete remission for 2 years

Keywords : chronic radiation dermatitis, immune response modifier, imiquimod, actinic keratoses, basal cell carcinoma, squamous cell carcinoma

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