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Fatal natural killer cell lymphoma arising in a patient with a crop of Epstein-Barr virus-associated disorders |
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European Journal of Dermatology. Volume 15, Number 6, 503-6, November-December 2005, Clinical report |
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 Free Article
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Author(s) : Yukiko Nitta, Keiji Iwatsuki, Hiroshi Kimura, Seiji Kojima, Tsuneo Morishima, Kazuhide Tsuji, Takashi Oono |
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Summary : Natural killer (NK) lymphoma in Asia is frequently associated with latent Epstein-Barr (EBV) infection. Unlike the adult cases, EBV-associated NK/T cell lymphomas in children are often preceded by various EBV-related disorders, including chronic active EBV infection (CAEBV), hypersensitivity to mosquito bites (HMB), virus-associated haemophagocytic syndrome (VAHS), and hydroa vacciniforme (HV)-like eruptions. Here, we report a 14-year-old Japanese girl who sequentially developed all the symptoms related to EBV-associated NK/T cell lymphoproliferative disorders in a 12-year clinical course. Our observations confirm the spectrum of EBV-associated cutaneous disorders and indicate the importance of long-term follow-up. |
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Keywords : EB virus, hydroa vacciniforme, haemophagocytosis, nasal lymphoma, natural killer cell, mosquito bite |
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Copyright © 2007 John Libbey Eurotext - Tous droits réservés