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Syringotropic cutaneous T cell lymphoma treated with PUVA therapy


European Journal of Dermatology. Volume 15, Number 4, 262-4, July-August 2005, Therapy

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Author(s) : Alessandro Venturini, Cristina Zane, Rosita Rodella, Carla Leali, Piergiacomo Calzavara Pinton, Fausto Zorzi

Summary : Syringotropic cutaneous T cell Lymphoma (SCTCL) is a rare localized variant of CTCL. It is characterized by erythematous papules that, at histological examination, show dense dermal infiltrates of atypical T cells, that are preferentially located around hyperplastic eccrine sweat glands and ducts, with absent or minimal epidermotropism. Its relationship with mycosis fungoides and other CTCLs is not clarified and is still under discussion. Several treatment approaches have been suggested, but therapeutic results are often disappointing. We report the case of a patient with typical clinical and histopathological features of SCTCL and an excellent response to PUVA therapy.

Keywords : PUVA therapy, syringotropic cutaneous T-cell lymphoma

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