Bulletin du Cancer
MENUA practical overview of aromatase inhibitors in postmenopausal women with hormone receptor-positive breast cancer Volume 92, numéro 4, Avril 2005
Illustrations
Department of Medical Oncology, London Regional Cancer Centre, 790 Commissioners Road, East London, Ontario N6A 4L6, Canada
- Mots-clés : adjuvant therapy, aromatase inhibitor, breast cancer, tamoxifen
- Page(s) : 10039-44
- Année de parution : 2005
Tamoxifen has been the standard adjuvant therapy for patients with breast cancer for the last several decades. Several recently completed adjuvant trials using aromatase inhibitors have shown the superiority of these agents over Tamoxifen or placebo, when used in postmenopausal women. The results from these trials present a challenging situation for practicing oncologists with regards to the choice, duration, sequence of therapy, follow up and side effects of aromatase inhibitors. We have discussed various management issues from a practical angle for oncologists to effectively use these agents, with an evidence-based approach.