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Transverse leukonychia in severe hypocalcemia


European Journal of Dermatology. Volume 14, Number 1, 67-8, January-February 2004, Clinical report

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Author(s) : Caterina FOTI, Nicoletta CASSANO, Vincenzo O. PALMIERI, Piero PORTINCASA, Anna CONSERVA, Michele LAMURAGLIA, Giuseppe PALASCIANO, Gino A. VENA

Summary : We report the case of a 26‐year‐old man with acral tetany and muscular cramps of the upper limbs associated with hypocalcemia caused by hypoparathyroidism and celiac disease. Physical examination revealed a transverse leukonychia which disappeared after treatment with calcium lactogluconate, calcium carbonate and calcitriol. Hypocalcemia may induce nail alterations with a double mechanism represented by angiospasm and disorganization of the hard keratin and of the integrin subunits.

Keywords : celiac disease, hypocalcemia, hypoparathyroidism, nails, transverse leukonychia

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