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CLA + T cells in cutaneous diseases |
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European Journal of Dermatology. Volume 14, Number 1, 13-8, January-February 2004, Review |
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 Free Article
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Author(s) : Luis F. SANTAMARIA‐BABÍ |
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Summary : The Cutaneous Lymphocyte‐associated Antigen (CLA) was originally described as a cell surface molecule preferentially found on T lymphocytes present in the skin. At the present time, a more complete and exciting picture is emerging thanks to the efforts of different research groups. The CLA antigen identifies a subset of memory effector T lymphocytes functionally involved in the pathogenesis of different T cell‐mediated cutaneous diseases. Research related to CLA + T cells is not only becoming a source of interesting data related to the pathological mechanisms of skin disorders, but also provides an innovative and selective approach to develop new treatments for T cell‐mediated diseases in dermatology. |
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Keywords : CLA, homing, skin |
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Copyright © 2007 John Libbey Eurotext - Tous droits réservés