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Granuloma faciale


European Journal of Dermatology. Volume 10, Number 4, 313-4, June 2000, Votre diagnostic !

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Author(s) : Deniz DEMIRCIOGLU, Gül BUKULMEZ, Aytaç GOKOZ

Summary : A 29 year-old male patient presented with a 2-month history of asymptomatic brown papules and plaques on the face, which had been gradually increasing in number. The patient's medical history was unremarkable for any other skin or systemic disease and he was not on any long-term medication. Examination of the skin revealed 8-10 well-circumscribed, dusky red-brown, indurated, 0.5-1.5 cm papules and plaques on the forehead and both cheeks (Fig. 1). Physical examination was otherwise normal. Histopathological examination of an excision biopsy specimen showed a dense mixed dermal infiltrate composed predominantly of neutrophils and eosinophils, also of plasma cells, lymphocytes and histiocytes. The subepidermal region and the adnexal structures remained uninvolved, thus the infiltrate was separated from the epidermis by a Grenz zone (Fig. 2). In the dermis some vessel walls were also infiltrated (Fig. 3). The epidermis was normal except for focal spongiosis and exocytosis.

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