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Coexisting linear and disseminated drug eruption: a clinical clue to the understanding of the genetic basis of drug eruptions


European Journal of Dermatology. Volume 11, Number 2, 89, March - April 2001, Editorial

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Author(s) : Rudolf HAPPLE, Isaak EFFENDY

Summary : In this issue, Remedios Alfonso and Belinchón Romero from Alicante describe an unusual drug eruption induced by ibuprofen [1]. Initially the patient showed unilateral linear lesions and 5 days later she developed a bilateral disseminated rash. The disseminated form of this reaction is very common, and there are several reports on linear drug eruption [2, 3]. An important feature of this case, however, is the combined occurrence of the two types of adverse reaction.

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