John Libbey Eurotext




Sign of Leser-Trélat associated with adenocarcinoma of the rectum
European Journal of Dermatology. Volume 11, Number 3, 251-3, May - June 2001, Cas cliniques
Free Article
Author(s) : M. Ginarte, D. Sánchez-Aguilar, J. Toribio
Summary : The acute onset and/or rapid increase in size and number of multiple seborrheic keratoses associated with internal malignancy is called sign of Leser-Trélat. Although some authors reject its existence, there are more than 80 well-documented case reports in the literature. Here, we report a 75-year-old man who presented with abrupt appearance of multiple seborrheic keratoses without any suspicious symptom of cancer. The screening for malignant neoplasms let us detect a rectal adenocarcinoma that was in a curative stage. This case-report illustrates a true sign of Leser-Trélat, and proves that these patients must be appropriately investigated for underlying malignancy.
Keywords : cancer, Leser-Trélat sign, paraneoplastic dermatosis, rectal adenocarcinoma, seborrheic keratoses.

Sign of Leser-Trélat associated with adenocarcinoma of the rectum