John Libbey Eurotext




Common variable immunodeficiency and eosinophilic fasciitis
European Journal of Dermatology. Volume 12, Number 1, 73-4, January - February 2002, Cas cliniques
Free Article
Author(s) : Mario DI GIOACCHINO, Silvio MASCI, Franco PAOLINI, Nicola VERNA, Domenico ANGELUCCI, Enrico CAVALLUCCI, Roberto PAGANELLI
Summary : The association of eosinophilic fasciitis and immunological defects is rare, especially hypogammaglobulinemia. We report a case of eosinophilic fasciitis occurring in a female, 53 years old, with common variable immunodeficiency. The diagnosis of common variable immunodeficiency was established by chance observation of persistently low levels of all immunoglobulin classes unrelated to protein loss or immunosuppressive treatment, one year after the appearance of eosinophilic fasciitis, which is usually characterized by hypergammaglobulinemia. Our description may prompt the investigation of an increased rate of simultaneous occurrence of eosinophilic fasciitis and common variable immunodeficiency.
Keywords : common variable immunodeficiency, eosinophilic fasciitis, hypogammaglobulinemia.

Common variable immunodeficiency and eosinophilic fasciitis