John Libbey Eurotext




Generalized eruptive histiocytoma of childhood associated with rheumatic fever
European Journal of Dermatology. Volume 9, Number 7, 548-50, October - November 1999, Cas cliniques
Free Article
Author(s) : Y. Matsushima, K. Ohnishi, O. Ishikawa
Summary : We describe a widespread papular eruption in a 5-year-old girl with rheumatic fever. Histological examination revealed a dense histiocytic infiltration in the dermis. On immunohistochemical studies, the cells were positive for vimentin, CD68, MAC387, alpha1-antichymotrypsin and lysozyme, but negative for CD1a and S-100 protein. Electron microscopic studies showed no Birbeck granules in their cytoplasm. A diagnosis of generalized eruptive histiocytoma of childhood was established. The skin lesions completely disappeared within 8 months.
Keywords : electronmicroscopy, generalized eruptive histiocytoma, pediatric case, rheumatic fever.

Generalized eruptive histiocytoma of childhood associated with rheumatic fever