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Generalized granuloma annulare and hepatitis B vaccination


European Journal of Dermatology. Volume 8, Number 6, 435-6, September 1998, Cas cliniques

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Author(s) : François WOLF, Pierre GREZARD, Frédéric BERARD, Gilles CLAVEL, Henri PERROT

Summary : As hepatitis B vaccination is becoming generalized in Europe, cutaneous adverse events are being more frequently reported in the literature. We report the first case of generalized granuloma annulare following hepatitis B immunization. A 51-year-old woman presented a generalized granuloma annulare one month after the one-year booster injection of the hepatitis B vaccine. The lesions resolved with sulfone therapy. We observed an identical recurrence three weeks after the five-year booster.

Keywords : generalized granuloma annulare, hepatitis B, vaccination.)

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