John Libbey Eurotext




Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma
European Journal of Dermatology. Volume 9, Number 1, 29-31, January - February 1999, Cas cliniques
Free Article
Author(s) : Arne KONIG, Gunther WENNEMUTH, H. Peter SOYER, Rolf HOFFMANN, Rudolf HAPPLE, Walter KRAUSE
Summary : We report a case of unusual cutaneous amyloidosis involving the vulva in a patient with multiple myeloma. Genital examination revealed a dense agglomeration of verrucous papules and pedunculated condyloma-like tumors. The correct diagnosis was established by immunohistochemical examinations that visualized large amounts of lambda light chains, whereas no reaction was detected for kappa light chains or human papilloma virus. In this way, the differential diagnosis of condylomata acuminata could be ruled out. Condyloma-like lesions have been described in patients suffering from multiple myeloma, but the present case is unusual because of the extensive involvement. Vulvar amyloidosis should be added to the list of possible presentations of myeloma-associated systemic amyloidoses.
Keywords : plasmocytoma, myeloma-associated amyloidosis, condyloma-like lesions.

Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma