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Launois-Bensaude syndrome and Bureau-Barrière syndrome in a psoriatic patient: successful treatment with carbamazepine


European Journal of Dermatology. Volume 12, Number 3, 267-9, May - June 2002, Cas cliniques

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Author(s) : Klaudia PREISZ, Sarolta KARPATI, Attila HORVATH

Summary : Authors report a 41-year-old male patient with multiple symmetric lipomatosis, who also had psoriasis. In addition he suffered from peripheral neuropathy, acro-osteolysis and malum perforans pedis fulfilling the criteria of Bureau-Barrière syndrome. Considering the severe peripheral neuropathy and the preliminary report on the efficacy of carbamazepine in psoriasis, a carbamazepine monotherapy was initiated for both indications. The psoriatic skin symptoms cleared within 6 weeks. The patient has continued this medication for 8 months without side effects. During that time his skin remained symptom free and the neuropathy has improved.

Keywords : Bureau-Barrière syndrome, carbamazepine, Launois-Bensaude syndrome, neuropathy, psoriasis.

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