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Pure cutaneous relapsing Langerhans cell histiocytosis in an adult


European Journal of Dermatology. Volume 8, Number 7, 501-2, October - November 1998, Cas cliniques

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Author(s) : Antonello Baldo, Amalia Vitiello, Giuseppe Argenziano, Gerardo Ferrara, Mario Delfino

Summary : The histiocytic syndromes represent a group of rare diseases characterized by the proliferation of the mononuclear phagocyte system cells. We report a case of recurrent class I histiocytosis with exclusive cutaneous localization in an adult. Our patient had a 3 cm ulcerated nodule located on the right cheek. Subsequently, new lesions appeared, all having the same clinical evolution characterized by spontaneous resolution with scarring. After a five year follow up no more lesions were observed. The histopathological examination, immunohistochemical profile and electron microscopy of the lesions indicated Langerhans cell histiocytosis.

Keywords : langerhans cell, histiocytosis.

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