John Libbey Eurotext




Milia-like idiopathic calcinosis cutis
European Journal of Dermatology. Volume 10, Number 8, 637-8, December 2000, Votre diagnostic !
Free Article
Author(s) : C. Schepis, M. Siragusa, A. Alberti
Summary : An 11 year-old boy affected by Down's syndrome (DS), confirmed by karyotype, was referred to us because he presented with a lot of whitish hard "pustules", ranged in size from 2 to 3 mm in diameter, distributed on his palms and fingers. The parents indicated that some elements, spontaneously eliminated through the skin, had a chalk appearance. The condition had been present for about a year. Laboratory findings were unremarkable with normal serum levels of calcium and phosphate. Histological examination of a biopsied lesion revealed hyperortokeratosis in the epidermis and, in the upper dermis, a round calcific nodule surrounded by a thin fibrovascular strip. What is your diagnosis? Which other perforating condition has been associated with DS?
Keywords :

Milia-like idiopathic calcinosis cutis