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Printable version |
Progress in Epileptic Spasms and West syndrome
Progress in Epileptic Spasms and West syndrome
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Franco Guzzetta, Bernardo Dalla Bernadina, Renzo Guerrini
2007
Series : Progress in Epileptic Disorders
Find out the books of Progress in Epileptic Disorders
ISBN : 978-2-74-200655-7
184 pages
Specialty : Neurology, Epilepsy
Published in : English
Contents (en)
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Price :
70.00 € |
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Since its first description (1841) the identity of West syndrome was deeply investigated and is now recognized as an epileptic syndrome in infancy (ILAE Task Force, 1989). West syndrome has become a paradigmatic model of an epileptic syndrome causing neurological deterioration (epileptic encephalopathy) and the object of a number of studies aimed at understanding the complex relationships between an epileptic disorder and neurodevelopment. Although the symptomatic triad (peculiar electrographic findings named hypsarrhythmia, brief tonic spasms, and arrest of psychomotor development) that characterizes the syndrome suggests a unique pathogenetic mechanism, causal heterogeneity heavily influences syndrome variability in terms of neurodevelopment, treatment choices, management and, possibly, electroclinical semiology. Important insights may arise for that might help developing models of epileptic encephalopathies in the basic sciences. However, a more immediate benefit may arise for clinicians in everyday practice. A group of clinical researchers recently met in Rome to discuss hot points concerning infantile spasms and West syndrome. Their contributions were collected and are presented in this book that we hope will contribute to the progress of knowledge of this paradigmatic epileptic disorder. CONTENTS: Nosological aspects of West syndrome West syndrome revisited. An introduction Infantile spasms and West syndrome: anatomo-electroclinical patterns and etiology Epileptic spasms: interictal patterns Epileptic Spasms: Ictal Patterns Spasms outside West syndrome New paediatric behavioural and electrophysiological tests of brain function for vision and attention to predict cognitive and neurological outcomes Developmental features in West syndrome West syndrome: epilepsy-induced neuro-sensory disorders and cognitive development Surgical treatment of West syndrome The medical treatment of infantile spasms ARGUMENTAIRE This book includes several contributions providing up to date information on electroclinical semiology, neurodevelopment, medical and surgical treatment of epileptic spasms and West syndrome, a condition for which knowledge appears to be always in progress.
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